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Hormone Imbalance

Conditions that can develop from hormonal imbalance, and will respond favourably to Naturone Progesterone Therapy

Diseases and Conditions That Can Develop from Hormonal Imbalance, and will Respond Favourably to Naturone Progesterone Therapy


Acne is an inflammatory disease of the skin which affects 85% of teenagers, most of whom are male. It can continue into adulthood. It occurs at a time of hormonal disruption and bringing the hormones back into balance with Naturone is recommended.


Hormone imbalance is a common cause of excessive aggression. Preventing aggression in those showing such imbalance is very often a matter of raising the progesterone in the blood level.

Adrenalin can be described as the aggression hormone. A drop in blood sugar levels makes the body release adrenalin which, in turn, causes the cells to release their stored sugar. Adrenalin is the 'fight, flight, fright' hormone. As progesterone cannot be used by a cell if too much adrenalin is in the blood, the limbic region of the brain is badly affected, as it has the greatest concentration of progesterone receptors in the body.

In any programme aimed at reducing aggression the limbic system cannot be ignored as it is an area in our brain controlling: rage, violence, panic, anxiety, sleep, hormones, depression, learning and our immune response.

Researchers have found that too low a level of cholesterol causes an increase in aggressive behaviour. Significantly, cholesterol is the precursor to progesterone.

To help control aggression it is essential to eat small, starchy, high fibre meals every 3 hours to keep blood sugar levels stable. Progesterone is required to stabilise blood sugar.


One in ten people over sixty-five and one in two over eighty-five has Alzheimer's. The first indications are confusion, depression, loss of memory and irritability. Some researchers believe it is caused by incorrect nutrition, pollution, oxidation and atherosclerosis (a disease in which deposits of fat cause the walls of t he arteries to thicken), leading to a lack of vital anti-oxidants to the brain, which in turn suffers damage from free radicals.

The result of all this is a lower level of vital neurotransmitters in the brain, in particular serotonin and acetyl-choline. Also implicated are high levels of calcium and aluminium.

Avoid all synthetic estrogen and aluminium products: cooking pots and pans, foil, toothpaste in aluminium tubes, carbonated soft drinks in aluminium cans, most deodorants, many antacids.

Balance calcium levels with magnesium and use large doses of Naturone and provide highly nutritious meals. Intellectual activities such as playing chess, bridge, completing crossword puzzles or regular social interaction, may also delay the onset, or reduce the severity, of Alzheimer's disease.

Auto-immune disease

Auto-immune diseases arise from an overactive immune response of the body against substances and tissues normally present in the body. In other words, the body attacks its own cells. Nearly 79% of auto-immune disease patients in the USA are women. They tend to appear during, or shortly after, puberty. It is not known why this should be the case, although hormone levels have been shown to affect the severity of some autoimmune diseases such as multiple sclerosis.

Lupus is an auto-immune disease causing inflammation of the connective tissue, with joint pain, fever and fatigue. There are three forms of lupus: (a) discoid (b) systemic and now (c) one caused by Aspartame, the synthetic sweetener used in most carbonated soft drinks. The latter is causing an epidemic of lupus and epilepsy in the USA.

Hormone imbalances induced by environmental poisons, especially the 'xeno-estrogens' are considered by some authorities to be a major contributory factor. Progesterone is a powerful anti-inflammatory and also acts to re-balance the disrupted hormones.

Users of HRT are more likely to get lupus than non users. estrogen is contra-indicated. Progesterone is the precursor hormone to your corticosteroids, including cortisone.  Pushing up your natural cortisone levels with Naturone therapy is very beneficial as cortisone is a very effective anti-inflammatory. Between 2-3ml/day should be applied, depending upon the severity of the disease. Immunity-boosting nutrition should also be used. 


The incidence of allergies,or intolerances, has increased from 2% to 20% of the population in the West. The link between progesterone and allergies is provided by the anti-inflammatory hormone, cortisone It has been found that the body’s reaction to an allergen, with the production of histamine, can be lessened if there are good levels of the anti-inflammatory hormone, cortisone.

Women who are susceptible to allergens find their reaction worse in the two weeks before menstruation and the five to ten years before menopause, when the level of estrogen is high compared to that of progesterone. Much of the 'allergic' reaction is nothing more than water retention and relief comes directly from dealing with this.

Cortisone is made in the adrenal glands from progesterone. Therefore maintaining adequate levels of progesterone in the blood will assist in ensuring an adequate supply of cortisone thereby assisting the body’s ability to resist allergies.


Researchers have found that alcohol lessens the ability of progesterone to break down the enzyme monoamine oxidase, thereby increasing depression. Keep the level of progesterone high if there is a problem with alcohol, particularly in women during the 8 days before menstruation.

Anxiety Disorders

Anxiety disorders are often debilitating chronic conditions, which can be present from an early age or can begin suddenly after a triggering event. They are prone to flare up at times of high stress, and can also be caused by a drop in blood sugsr.

Anxiety disorders are characterised by mild to severe mental (emotional) and physical effects.

Mental: agitation, agoraphobia, apprehension, constant worry, endless crying, depression, feeling stressed and/or overwhelmed, irrational fears, irritable, irrational behaviour, lack of self confidence and esteem, low tolerance to stress, nervousness, panicky feelings or panic attacks, difficulty relaxing, emotional balance upset, tension.

Physical: butterflies in the stomach, breathing difficulties, cold and/or clammy hands or skin, cravings for sweet things, dizziness, exhaustion/fatigue, headaches, hot flushes/sweating, itching skin, jittery, lump in throat, misty vision in eyes, muscle weakness, nausea, rapid heart beat or palpitations, shaking or trembling, shortness of breath, stiff/uptight, 'stomach in knots', tight chest, tremors.

The body responds to any stress, either mental or physical in the same way...

The stress hormones cortisol, noradrenaline and adrenaline rise, causing restlessness, nervousness, jitters and other non-specific and non-directed signs of agitation. Blood is directed away from periphery blood vessels and directed to the heart and major muscles, blood pressure increases, as does heart rate.The immune system, digestion, hormones, neurotransmitters etc. are suppressed.

In other words the body goes on hold, apart from the heart and legs, until all danger has been dealt with. Fine when being chased by a sabre tooth tiger, but harmful if not!

This outpouring of adrenalin causes sugar (glycogen) stored in cells in the body, particularly the liver, to pour into the blood to give energy. As the sugar drains out it is replaced by water, causing bloating and weight gain. Too much adrenalin can bring on an attack of panic, migraine, epilepsy and some of the anxiety attack symptoms above.

An increase in cholesterol and triglycerides also occurs, if too much insulin is released. Blood sugar drops sharply, leading to many of the above symptoms. If at this point no food is eaten, to prevent the sugar dropping too low, the adrenal glands again pump out adrenalin to bring stored sugar into the blood, and so a vicious circle is started.

Adrenalin, apart from making the heart race, produces the following anxiety attack symptoms...

FIGHT: Aggression, Irritability, Rage, Violence
FLIGHT: Avoidance, Mental confusion, Withdrawal, Fatigue
FRIGHT: Anxiety, Apprehension, Depression, Panic

With the drop in levels of neurotransmitters, particularly GABA *(our major calming neurotransmitter) and serotonin (our major 'happy' neurotransmitter) and a drop in progesterone levels, agitation, nervousness, panic attacks or panicky feelings are produced. It is essential to replace these missing nutrients to prevent further agitation.

Natural treatment of anxiety attack symptoms

Progesterone is known as a neurosteroid, because it is synthesized in the central nervous system and affects nerve functioning, and therefore mood and behavior.

Progesterone has been found to enhance GABA's calming affect and suppress the 'excitatory glutamate response'. The anti-anxiety affect has been noticed within three to ten minutes, whether injections or topical progesterone had been used as the means of administration.

The anti-anxiety response is similar to that found after the administration of benzodiazepine drugs, but of course with no addictive risks.

Unstable blood sugar can cause anxiety and panic attacks. It is imperative to stabilise this.

Stress, particularly sudden, can bring on an attack of anxiety/panic. It's difficult to avoid stress, but if blood sugar is stable and both progesterone and GABA are being used, the stress response will be much less severe.

Blood clots

Estrogen thickens blood and causes an increased risk of clots.

Avoid all forms of estrogen and use approximately 20mg/day of Naturone, as this reduces the risk of clots. Also take between 15 to 75ml of Omega 3

Blood sugar; low - (hypoglycemia) and high (hyperglycemia)

One of the many functions of progesterone is blood sugar regulation in all vertebrates. Irregular levels of blood sugar can result in a number of conditions ….bloating, weight gain, panic attacks, migraine, epilepsy etc.

Breast Cysts

These are caused by an imbalance in estrogen and progesterone**, so applying progesterone cream helps immediately.

Breast tenderness

Excessive estrogen relative to progesterone causes water to be retained in the breasts, which results in swelling and pain. Rubbing Naturone directly onto the breasts relieves this.

Cancer of hormonally sensitive tissue

As progesterone de-activates the Bcl-2 gene (the onca gene which is activated by estrogen) and activates the p53 gene (a protective gene that gives the right message to cells), it is important to supplement with Naturone.

Women with low levels of progesterone have a greater chance of getting breast cancer with 10 times a greater chance of dying from all cancers. Breast cancer recurrence after a mastectomy is more likely if the surgery is performed in the first half of the cycle when estrogen is dominant than in the second half. The Pill increases the risk of getting cervical cancer as does HRT. Tamoxifen, a weak estrogenic drug used in the treatment of breast cancer, is classified as a carcinogen. It causes an increase in both endometrial and liver cancer. The dose of Naturone is dependent on the levels of estrogen in the body, and will vary from 25mg in a post menopausal woman to 50 mg in a fertile female.

There are many factors associated with hormonal imbalance and increased risk of breast cancer including: Declining levels of progesterone with age and/or with removal of the ovaries in hysterectomy. Environmental, “xeno”-hormones in the form of pollutants and pesticides, oral contraceptives, and synthetic hormone replacement therapy.

These factors can contribute to an excess of estrogen in the body known as “estrogen dominance.” Since estrogen stimulates cell growth, a predominance of it especially in the absence of adequate levels of progesterone (common in the menopausal years with the waning of ovulation), presents an increased risk of cancer, particularly in the breast.

Chronic fatigue

Muscular weakness; exhaustion; confusion; procrastination; lethargy; excessive yawning; lack of libido; shortness of breath and joint pains are symptoms of fatigue. As stress hormones are made in the adrenal glands from progesterone, a lack of progesterone usually due to adrenal exhaustion, post natal low levels of progesterone or annovulatory cycles lead to the above problems manifesting themselves. High doses of Naturone (up to 200mg) are helpful 

Cold hands and feet

Progesterone helps to thin blood thereby increasing circulation, which helps with this condition  


Progesterone, because of its ability to reduce water retention, can cure constipation.

Cracked Heels

Cracked heels respond favourably to application of Naturone cream to the skin, anywhere on the body.


Progesterone has a natural Valium-like effect which helps with depression.  It also naturally balances the seratonin levels.  Seratonin is known as the “happy” hormone.


Endometrial cell growth is stimulated by estrogen.  Endometriosis occurs when these cells are now growing in areas other than the endometrium, such as in the walls of the uterus, anywhere in the pelvic area, bladder, lungs, liver brain and rectum. These cells cause pain and because they are hormonally sensitive can cause bleeding.  High doses of Naturone, 200mg are needed to keep this under control and slowly but surely the condition should disappear. Naturone also eases the pain.

Fertility and other female problems


Progesterone is the pro-gestation hormone and is vital for the survival of the fertilised egg, maintains the secretory endometrium and nourishes the ovum and embryo.  Low levels of progesterone cause miscarriages.  Many pregnancy problems are due to an under-developed placenta and symptoms will be greatly reduced if progesterone is used throughout the pregnancy.     


This polluted environment has wreaked havoc with human fertility.  Not only has the sperm count dropped by more than 50% in the West, but the endocrine disruptors have effected women’s fertility from her foetal days.  Anorexics, long distance runners and ballet dancers often cease menstruating if their body fat drops below 20%.  Defective Luteal phase which happens in the last 2 weeks of the month results in the inability of the egg to embed in the uterine lining.  This problem is directly as a result of low levels of progesterone. High doses of progesterone are needed as a supplementation , this can be reduced very slowly during pregnancy once the placenta takes over the role of producing large amounts of this hormone.


Fibroids are benign, usually painless tumours found in the uterus.

Estrogen dominance, an imbalance caused by excess estrogen in the relative absence of progesterone, can cause the uterine lining to grow unchecked. This can lead to the growth of tough fibrous, non-cancerous lumps called fibroids. While the average fibroid is an undetectable lump in the wall of the uterus, about the size of a hen’s egg, larger fibroids often cause irregular bleeding and heavy or painful periods. Fibroids are the most common physical reason for excessive bleeding during menstruation.

The cause again is estrogen dominance and therefore Naturone 20 to 200mg/day helps control this condition.  They may take up to 6 months to disappear. A hysterectomy is not necessary.

Fibroids can grow dramatically during perimenopause when they are stimulated by hormonal imbalances and fluctuations in the body. Large fibroids secrete estradiol, the most potent form of estrogen, leading to estrogen dominance. Taking appropriate steps to maintain a proper balance of estrogen to progesterone is especially important.

Hair loss & excessive facial hair in women

With declining progesterone levels in the 5 to 10 years prior to menopause, the body responds by producing alternative adrenal hormones which have some male like effects. The two most obvious results of this are male pattern baldness and facial hair.

Applying 20mg/day of progesterone causes facial hair to drop off within weeks, but hair on the head will take up to 6 months to grow.


Heart Disease

Blood clots
Oestrogen thickens blood and causes an increased risk of clots.

Avoid all forms of oestrogen and use approximately. 20mg/day of progesterone, as this reduces the risk of clots. Also take between 15 to 75ml of Omega 3.

Heart attacks

Oestrogen causes water retention that increases the blood pressure. High blood pressure increases the risk of both heart attacks and strokes. A normal blood pressure irrespective of age should be 120/80. A healthy cholesterol level should be 190 -210mg/dl. Oestrogen also accelerates the aging of collagen, weakening the walls of the arteries. Progesterone is a natural diuretic and protects the cardio-vascular system. Oestrogen promotes fat synthesis and blood clots while progesterone increases the burning of fats. It is also very effective at preventing palpitations or arrhythmias. Progesterone counteracts the effects of oestrogen and is known to relax coronary arteries that have gone into spasm, it also normalises blood clotting and brings down blood pressure by acting as a diuretic. 20 to 200mg/day of progesterone will be needed depending upon the severity of the problem. 


Inflammatory diseases

There are about 100 diseases that produce either inflammation in the connective tissues or degeneration of these tissues. These diseases include Alzheimer's, arthritis, asthma, atherosclerosis, Crohn's disease, colitis, dermatitis, diverticulitis, hepatitis, irritable bowel syndrome (IBS), lupus erythematous, nephritis, rheumatoid arthritis, Parkinson's and ulcerative colitis. Inflammation is the end result of long term stress. Progesterone is an excellent anti-inflammatory, being the precursor to cortisone, so rubbing the cream on to the painful joints has helped many people. 20 to 200mg/day should be used until the symptoms are under control and then the amount used adjusted. Avoid all forms of estrogen.

Libido loss

This, including loss of femininity/masculinity and impotence are helped with Naturone.

Male Fertility

The polluted environment in which most of us live has also created havoc with male fertility.  The sperm count amongst many men in cities in the West has dropped by more than 50%. As progesterone is a precursor to testosterone, its use can also be of great benefit to men.


Menopause occurs naturally in mature women, with the average age of onset being 51. Some women are fertile into their 60’s whilst menopause has been recorded in women as young as 19. Strictly speaking menopause only starts once the periods have ceased altogether but symptoms like hot flushes, bloating and vaginal dryness can be experienced before the periods stop. This is known as peri-menopause and often the symptoms are worse earlier than later.

A normal female baby is born with several million eggs already developed in her ovaries. After puberty the eggs are released monthly during the female cycle and many die and are re-absorbed. By the time she reaches her early fifties, the number of eggs remaining has reduced greatly and she enters a period of anovulatory cycles. Because ovulation does not take place, the second phase of the cycle does not happen so progesterone is not released by the ovaries. It is this drop in the levels of progesterone that causes most of the symptoms associated with menopause. Remember that during the first half of the cycle, estrogen is still produced so it is really the imbalance between low progesterone and high estrogen levels that causes the problems.

Treatment with Naturone natural progesterone cream, which is the bio-identical molecule to that produced by the body, relieves those symptoms. Many women are prescribed HRT at this time, but need to be aware that this contains progestins that are synthetic derivatives of the ‘real’ progesterone and can have negative side effects.

Menopause may also be induced surgically through a hysterectomy, the removal of the uterus and sometimes the ovaries as well. If the ovaries are not removed at the same time they generally atrophy within two to three years. This radically interrupts the production of estrogen and progesterone. Because progesterone is the mother hormone from which the estrogens are made (as well as the cortico-steroids and testosterone) treatment with Naturone natural progesterone cream allows for the supplement of both the progesterone and estrogen.

Diet also plays an important role in whether a woman ‘sails through’ menopause or not. It is advisable to avoid all processed foods containing sugar and refined grains as excess sugar can bring on hot flushes. Xylitol and stevia are sensible alternatives to sucrose, and any sweetener containing aspartame should be avoided. Stimulants such as coffee and black tea should be replaced by herb teas. Choose foods that are natural and unprocessed and contain both protein and fibre. Avoid foods containing preservatives, flavourants and colourants. And of course remember to drink 8 glasses of water daily.

Miscarriages and infertility

There are a number of different factors that contribute to infertility such as venereal disease, genetic abnormalities, very low body mass caused by bulimia, anorexia and a deficient diet, stress, a low sperm count and hormonal imbalance. This text will concentrate on the last of these.

The normal fertile female menstrual cycle is usually 28 days with variations from 21 to 36 days. Each step of this cycle is controlled by hormones. Any disturbance to the balance of these hormones can disrupt the normal cycle leading to infertility and miscarriage.

At puberty the child starts to develop into a man or woman. This initially results from the action of the two hormones estrogen and testosterone- boys produce more testosterone (facial and pubic hair, deepening of the voice, muscle development, etc) and girls more estrogen. Estrogen causes the breasts to develop and fat deposits to appear particularly on the hips and thighs-‘puppy fat’. Only once ovulation starts is progesterone produced which counteracts the effects of the estrogen, reducing the ‘puppy fat’. About two years after the onset of puberty, menstruation starts. This cycle is controlled by four hormones; Follicle stimulating hormone (FSH), estrogen, Lutenising hormone (LH) and progesterone.

  1. At the beginning of the cycle, Follicle stimulating hormone (FSH) stimulates the ovary to make estrogen as well as causing an egg and the follicle surrounding it to mature. The estrogen stimulates production of the blood supply to the uterus and growth of the tissue within the uterus.
  2. Half way through the cycle, Lutenising hormone (LH) is released by the pituitary gland, stimulating the follicle to break open and release the egg, which travels down the fallopian tube.
  3. The ruptured follicle, now known as the corpus luteum, starts to produce progesterone which prepares the lining of the uterus (endometrium) so that a fertilised egg may be embedded in it, resulting in conception and pregnancy.
  4. If conception does not take place, the levels of progesterone drop and the lining of the uterus comes away during the process of menstruation.

The balance between estrogen and progesterone throughout the cycle is what creates a healthy reproductive system in females. Insufficient progesterone during the second half of the cycle is known as ‘defective luteal phase’. Recent research has shown that in many fertile females, although fertilisation takes place regularly, conception, does not because the low levels of progesterone in the female are insufficient to prepare the lining of the uterus to receive the embryo.

If there are high levels of estrogen in the body, a situation known as estrogen dominance occurs. Correcting estrogen dominance is essential for pregnancy to occur. Estrogen dominance may result from any or all of the following:

  • Animals that supply us with the meat we eat may have been fed hormones to increase growth rate
  • Crops are frequently sprayed with insecticides which are mostly estrogenic
  • Most cosmetics use cold cream as their base; cold cream is derived from petro-chemicals
  • Many women use the contraceptive Pill and at menopause are prescribed Hormone Replacement Therapy(HRT)
  • Stress
  • Drinking recycled water in cities from which all the estrogen has not been removed
  • Vehicles that burn petrol and diesel emit exhaust fumes that act as xeno-estrogens; we breathe in this air
  • Plastics in which we wrap or carry our food are products of the petro-chemical industry.

Hence the use of a good quality, natural progesterone cream like Naturone, applied to the skin and absorbed transdermally (through the skin) can be used to increase the possibility of conception and decrease the likelihood of a miscarriage.

As the pregnancy proceeds, the placenta starts producing increasing amounts of progesterone; up to 300mg/day. However, it is not wise to stop applying the Naturone as a sudden drop in the levels of progesterone may have a negative effect. 


Osteoporosis is the weakening of the bones.  It is characterized by a decrease in bone mass and deterioration in bone tissue which makes bones fragile and creates a high risk of bone fractures.  Bone health results from two continuous processes; Firstly, cells known as Osteoclasts break down old and damaged bone tissue. This activity is influenced by estrogen levels.  In the second step Osteoblast cells lay down new bone tissue.  Progesterone is the only known factor that stimulates osteoblast activity. Without this the bones become porous or sponge-like and brittle.

Fractures of the hip, forearm and lower spine are increasingly common and are striking men as well as women at a younger and younger age.  Osteoporosis is rapidly becoming epidemic. 

Other contributing factors in Osteoporosis are:-

  1. Diet.  Foods that are bad for our bones are acid causing foods such as sugar, refined carbohydrates and excess protein as in meat (meat is made up of amino acids). These foods affect the pH of the body, thus causing loss of calcium from the bones to maintain a balanced pH.
  2. Malnutrition,  which is rife in the west amongst the wealthy because of junk food diets, and weight loss programs and anorexia
  3. Habits such as smoking and drinking
  4. Medical drugs.  Many drugs affect our bones, such as antacids, lithium, chemo therapy, anti-convulsants, corticosteroids, thyroid drugs, diuretics and antibiotics.
  5. Excessive exercise without adequate supplementation of nutrients.
  6. Stress, as it causes hormonal imbalances which in turn cause calcium to be lost from the bones.
  7. Weak digestion limits bone health too.  This often occurs as we age.

In 1981, Dr John R Lee began what is now a landmark study of progesterone in the treatment of osteoporosis:  Every one of the sixty three women treated with progesterone had an increase in bone mass.  Furthermore, in many cases this increase was substantial, far greater that what has been achieved with other osteoporosis therapies.

Dr Earl Mindel author of "The Vitamin Bible" states in his July 96 issue of the Mindel Letter that osteoporosis drugs such as Fosomax, Didronel and Floride do not prevent or reverse osteoporosis, and can cause serious side effects.  What these drugs do is temporarily create denser bone that looks better on X-rays but is of poor quality and causes increased risk of fracture!

Dr Mindel goes on to say that "If you're at risk for osteoporosis, remember that the only thing now to actually prevent and reverse it is natural progesterone, preferably used as a skin cream.  And don't forget to get plenty of weight bearing exercise."

To add to what Dr Mindel says, it is vitally important to take supplements to build our bones, as the nutritional content of our food these days is deficient.  Take both vitamins and mineral supplements, making sure you get adequate Vit K as well as a balanced calcium , magnesium  and zinc supplement


PMS is a state of estrogen dominance or progesterone deficiency which will be relieved by use of Naturone

Period pains and ovulation cramps

Pain during menstruation, known as dysmenorrhea, is now acknowledged to be an imbalance of hormones. Endometriosis also causes pain at menstruation.

Apply 25 to 200mg/day of progesterone rubbed directly onto the abdomen.

Polycystic Ovaries

Polycystic ovaries occur when numerous growths/cysts develop on the ovaries. This is commonly associated with a hormonal imbalance such as estrogen dominance and/or an excess of male hormones. In many cases, these cysts are benign and can shrink or even disappear when the hormone imbalance is corrected. The only reason for removal of the ovaries is if they are cancerous.

Post Natal Depression

One of the factors of post natal depression is the sudden drop of progesterone once the baby is born.

When you consider that a women in her last trimester of her pregnancy is producing up to 400mg of progesterone via the baby's placenta, after the baby is born and the placenta is expelled, the progesterone factory is literally turned off. Perhaps it is significant that man is the only mammal to not eat the placenta which would supply the new mother with a large dose of progesterone to start off her motherhood.

Most women will be familiar with the term 'baby blues'. With the sudden withdrawl of progesterone, depression can be triggered, known as post-natal depression. This can vary for every women in the time of onset, severity, and duration. And for other women, it can be insidious, undiagnosed and left untreated for many years after the baby is born. But it's now recognised that women generally do go through a brief period of depression following the birth of their child which they usually get over in no time. Now, with the discovery of progesterone supplementation, it has been such a breakthrough in defeating post-natal depression.

As stated above, during the course of a woman's pregnancy, production of progesterone (via the placenta) will peak at levels of 350 to 400 milligrams a day. Following delivery, her placenta-derived progesterone will plummet. The only source of progesterone at that time would be the adrenal glands, assuming mum is not in a state of adrenal exhaustion. Our observation has been that progesterone has provided women with a 'happy' and safe solution for mum and her baby, and has not interfered with her milk production. Some women have even commented that they've been able to relax, cope better and enjoy the experience of motherhood for the first time, where their previous accounts battling depression and their refusal to resort to medication, or the side effects of the medication they were encouraged to take may have left them feeling quite cheated of the whole mothering experience.

Women share with us their feelings of shame and failure associated with post-natal depression, particularly when it has not been explained to them that post-natal depression is the result of a hormone imbalance of which they have no control over. There are cases where post-natal depression is very severe and requires you to be under the care of a specialist. If you wish to incorporate natural progesterone using high doses, you will need to find a doctor who will support this therapy. Dr Katharina Dalton is well known for her work and research in the treatment of post-natal depression (and PMS) using very high levels of progesterone (100-300mg) daily.

Note, please take precaution during lactation that you do not become pregnant. Breast feeding in conjunction with natural progesterone is not a substitute for contraception. Some women are, by nature, very fertile.

Skin disorders

These include: acne; facial pigment; erythema; herpes simplex; urticaria; psoriasis; neurodermititis; rosacea; seborrhea; keratoses; dryness; early aging; excessive bruising, all of which can occur due to a lack of progesterone. Use of Naturone improves all the above conditions.

Thyroid problems

Many so called thyroid problems are nothing more than estrogen dominance, as estrogen blocks the effective action of the thyroid hormones.  Doctors will usually administer the drug “Eltroxin”, but in a lot of cases progesterone cream is all that is needed to correct this imbalance.

Hypothyroidism or low thyroid is more common in women than men often occurring during the perimenopausal and postmenopausal years. Approximately 26% of women in or near menopause are diagnosed with hypothyroidism. When estrogen is not counterbalanced with progesterone, a predominance of estrogen can inhibit the action of thyroid hormone at the cell level. Saliva hormone testing often reveals that women who are estrogen dominant tend to have menopausal symptoms associated with typically low thyroid symptoms such as: feeling cold all the time; weight gain or being unable to lose weight; thinning hair; sleep disturbances and fatigue; mood swings, depression; mental confusion; hair loss and low libido.




  1. Side effects of natural progesterone
  2. What is progesterone?
  3. Why do we need to supplement our progesterone?
  4. Why not just use the progestin Provera as prescribed by some doctors?
  5. What is estrogen dominance?
  6. Does a pre-menopausal woman need progesterone cream?
  7. What is progesterone made from?
  8. Is progesterone cream safe?
  9. Wouldn't it be easier to just take a progesterone pill?
  10. Why NATURONE?

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