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Conditions that can develop from hormonal imbalance, and will respond favourably to Naturone Progesterone Therapy

Medical Reports


The Greatest Experiment Ever Performed on Women


In 2002, 20 million American women woke up and read the shocking news that combined hormone therapy, instead of offering protection from major diseases, actually increases the risk for breast cancer, heart attack, blood clots and stroke. Since then, we've also learned that these drugs offer no benefit for mood or sexual function and double the risk for developing dementia.

Some women, such as Joan Levinson of Berkeley, have greeted this news as a confirmation of a lifelong scepticism of taking unnecessary drugs. "When I reached menopause," Levinson says, "every doctor was ready to pull out the prescription pad for pills. I always said no. Reason? I believe in the body and that the Original Designer knows better than mere mortals who have gone to medical school. So, barring life-and-death medical situations, I usually do not allow wonder drugs to enter my sacred body."

But many women, for their own reasons, followed their doctor's recommendation and now, with varying degrees of difficulty, are weaning themselves off hormone pills.

Not surprisingly, some women now feel betrayed. The drug industry and many doctors had promised that hormone therapy would give post-menopausal women protection from serious medical problems -- not to mention the glow of eternal youthfulness.

How could the drug industry and medical profession have been so wrong?


This is the question that Barbara Seaman addresses in her forthcoming book, "The Greatest Experiment Ever Performed on Women" (Hyperion, 2003), a splendid history that exposes how menopause was transformed into a medical problem and who was responsible for identifying hormone therapy as the medication for this "disease." Seaman is a veteran health advocate and journalist who, in 1971, authored the famous "Doctor's Case Against the Pill," an inquiry into the dangers posed by birth control pills.

In a telephone interview from New York, she explained why she wrote this book. "I have a compulsion to disclose the true history of these drugs and the hidden knowledge that was kept from users. Many of the risks, especially blood clots, had long been known by research scientists. Research on hormone therapy was mostly smoke and mirrors and science."

Seaman blames this "great experiment" on specific scientists, researchers and drug companies who created "one of the most elaborate promotional and advertising campaigns in the history of the media."

The drug industry, in particular, not only lobbied doctors, but also subsidized research that would support their claims. They also tried to discredit medical researchers, doctors and health advocates who raised serious doubts about tampering with women's hormones.

Seaman notes that "two-thirds of the women who have gone off hormones are doing just fine. Now we need research that can identify which women really need hormone therapy, instead of giving it to everyone who turns 50."

In addition, she also warns that "everyone's desperately looking for alternatives." So we should expect a growth industry in all kinds of alternatives -- including "the estrogen patch," herbal supplements, and topical and inserted use of hormonal products.

Trust only a herbal product that has been used for centuries and has known benefits, a product that is a food, or a supplement or topical application that has the identical molecule to that which your body produces naturally.

What lessons should we learn from this cautionary tale?


Cynthia Pearson, executive director of the National Women's Health Network, says, "We have to ensure that our regulatory agencies have the resources they need to protect us and we have to demand that doctors prescribe based on evidence, not on drug company marketing."

The range of acceptable alternatives are:-

a.Herbal Products that are well known for their balancing effects.
b.Natural Vitamins and Minerals and Organic food supplements
c.Natural Progesterone topical creams provided they are in a natural based cream, and are NOT Wild Yam.

Hormone replacement therapy study halted, Increased risk of breast cancer a factor, government says. July 9, 2002 Posted: 3:07 PM EDT (19h07 GMT)


WASHINGTON (CNN) -- In a move that may affect millions of women, U.S. government scientists Tuesday stopped a major study of hormone replacement therapy on the risks and benefits of combined estrogen and progestin in healthy menopausal women, citing an increased risk of invasive breast cancer.

The estrogen and progestin trial study involved 16,608 women ages 50 to 79 with an intact uterus. A major objective of the trial study was to explore the effect of estrogen and progestin on the prevention of heart disease and hip fractures and any associated change in risk for breast and colon cancer.

About 6 million women in the United States are taking estrogen and progestin for various reasons, including relief of menopausal symptoms and long-term use for the prevention of heart disease and brittle bones.

"We have long sought the answer to the question: Does postmenopausal hormone therapy prevent heart disease and, if it does, what are the risks? The bottom-line answer from [the Women's Health Initiative] is that this combined form of hormone therapy is unlikely to benefit the heart," said Dr. Claude Lenfant, Director of the National Heart, Lung and Blood Institute of the National Institutes of Health, in a statement. They also found increases in coronary heart disease, stroke and pulmonary embolism.

"Women with a uterus who are currently taking estrogen plus progestin should have a serious talk with their doctor to see if they should continue it," said Jacques Rossouw in a statement. Rossouw is acting director of the Women's Health Initiative, which sponsored the study.

"If they are taking this hormone combination for short-term relief of symptoms, it may be reasonable to continue since the benefits are likely to outweigh the risks," Rossouw continued. "Longer term use or use for disease prevention must be re-evaluated."

A statement from the institute noted the benefits of estrogen combined with progestin, "including fewer cases of hip fractures and colon cancer, but on balance the harm was greater than the benefit.” The cardiovascular and cancer risks of estrogen plus progestin outweigh any benefits -- and a 26 percent increase in breast cancer risk is too high a price to pay, even if there were a heart benefit. Similarly, the risks outweigh the benefits of fewer hip fractures.”

"Menopausal women who might have been candidates for estrogen plus progestin should now focus on well-proven treatments to reduce the risk of cardiovascular disease, including measures to prevent and control high blood pressure, high blood cholesterol and obesity," Lenfant continued.

The study further clouds an issue that already was confusing for many women. Contradicting research about the risks and benefits of hormone replacement therapy has been periodically released for years. The only consensus among experts is that the decision is an individual one since every woman's lifestyle issues and risk profile is different.

In a statement, Garnet Anderson, a biostatistician who led the analysis at the Fred Hutchinson Cancer Research Center in Seattle, Washington, said, "The trial was stopped at the first clear indication of increased risk." Anderson also said that, at that point, there was no indication of increased risk for breast cancer in the estrogen-only group.

NEWS: Study says HRT increases stroke risk


NOTTINGHAM, England, Jan 06, 2005 (United Press International via COMTEX) -- Britain's University of Nottingham has found hormone replacement therapy is associated with an increased risk of stroke, especially ischaemic stroke. The results, published on British Medical Journal Online, support previous trials that have suggested a link between HRT and stroke.

HRT includes treatments of estrogen or estrogen and progestins for women to relieve symptoms of menopause. The researchers reviewed evidence from 28 completed trials involving 39,769 individuals. HRT was associated with an overall 29 percent increase in the risk of stroke, especially ischaemic stroke, which is caused by an insufficient blood supply to the brain. The severity of stroke also increased with HRT.

The authors said it remains unclear why HRT should increase ischaemic stroke and its severity when some previous studies have suggested it might have a protective effect. However, they said, given their findings, HRT cannot be recommended for the primary or secondary prevention of stroke. Keep in mind that these results are NOT inclusive of human-identical hormone replacement therapy.

NEWS: Estrogen affects gallbladder disease risk


IOWA CITY, Iowa, Jan 18, 2005 (United Press International via COMTEX) -- University of Iowa researchers Tuesday reported estrogen therapy can increase a post-menopausal woman's risk of gallbladder disease. The study, published in the Journal of the American Medical Association, examined data from the Women's Health Initiative, which included two clinical trials conducted at 40 U.S. centers.

The 22,579 women involved were ages 50-79 and had not had their gallbladders removed. Women who had undergone a hysterectomy were given conjugated equine estrogens or a placebo. Women who had not had hysterectomies were given estrogen plus progestin, a commonly prescribed treatment for menopausal symptoms.

The researchers found both trials showed a greater risk of gallbladder disease or surgery among women who took estrogen -- a 67 percent increased risk with use of conjugated equine estrogens and a 59 percent increased risk with use of estrogen and progestin.

Both trials indicated a higher risk for inflammation of the gallbladder -- an 80 percent increased risk conjugated equine estrogens and a 54 percent increased risk with estrogen and progestin.

comment.....
Dr Lee puts the blame for Gall Bladder disease 100% with oestrogen dominance, caused primarily from drugs or other Xeno-oestrogens.


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